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Cocaine also blocks sodium channels, thereby interfering Along with the propagation of motion potentials;[113][seventy two] thus, like lignocaine and novocaine, it acts as a local anesthetic. It also features on the binding web-sites for the dopamine and serotonin sodium dependent transportation spot as targets as independent mechanisms from its re

Palmer instructed Kerner the cocaine wasn't his and that his uncle was staying at your house, but Kerner testified he could obtain no man or woman by that identify in regional law-enforcement databases.Naloxone is often a medication that may address an opioid overdose when presented straight away. It really works by speedily binding to opioid recep